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TMEM45A Antibody

  • 货号：
    CSB-PA023842LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA023842LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA023842LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A2780 cells using CSB-PA023842LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TMEM45A Polyclonal antibody
  • Uniprot No.：
    Q9NWC5
  • 基因名：
    TMEM45A
  • 别名：
    TMEM45A; DERP7; DNAPTP4; Transmembrane protein 45A; DNA polymerase-transactivated protein 4; Dermal papilla-derived protein 7
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 45A protein (171-217AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TMEM45A Antibody (CSB-PA023842LA01HU)，的标记方式是Non-conjugated。对于TMEM45A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023842LB01HU TMEM45A Antibody, HRP conjugated ELISA
    FITC CSB-PA023842LC01HU TMEM45A Antibody, FITC conjugated
    Biotin CSB-PA023842LD01HU TMEM45A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. our study suggests that TMEM45A may work as an oncogene and a new effective therapeutic target for glioma treatment. PMID: 26722455
    2. knockdown of TMEM45A also inhibited cell adhesion as well as cell invasion. More importantly, suppression of TMEM45A notably downregulated the expression of TGF-b1, TGF-b2, RhoA and ROCK2. PMID: 25872785
    3. TMEM45A expression is correlated to epidermal keratinization PMID: 24689342
    4. Data suggest that high levels of TMEM45A expression in tumors may be indicative of potential resistance to cancer therapy, making TMEM45A an interesting biomarker for resistance. PMID: 22954140
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    TMEM45 family
  • 数据库链接：

    HGNC: 25480

    KEGG: hsa:55076

    STRING: 9606.ENSP00000319009

    UniGene: Hs.658956