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TMEM176B Antibody

  • 货号：
    CSB-PA023758LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TMEM176B antibody at 8µg/ml + Human placenta tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 30, 26 kDa
      Observed band size: 30 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA023758LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA023758LA01HU at dilution of 1:100
    • Immunofluorescent analysis of LO2 cells using CSB-PA023758LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：

    To produce the TMEM176B antibody, a rabbit was first immunized with the recombinant human transmembrane protein 176B (1-64aa). Following this, the rabbit serum was collected and the antibody was isolated and purified through protein G affinity chromatography.

    The resulting antibody showed high purity levels of up to 95% and displayed reactivity solely with human TMEM176B protein. Quality verification tests were conducted on the rabbit anti-human TMEM176B polyclonal antibody, including ELISA, WB, IHC, and IF, confirming its suitability for use in various applications.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TMEM176B Polyclonal antibody
  • Uniprot No.：
    Q3YBM2
  • 基因名：
    TMEM176B
  • 别名：
    TMEM176B; LR8; Transmembrane protein 176B; Protein LR8
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 176B protein (1-64AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TMEM176B Antibody (CSB-PA023758LA01HU)，的标记方式是Non-conjugated。对于TMEM176B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023758LB01HU TMEM176B Antibody, HRP conjugated ELISA
    FITC CSB-PA023758LC01HU TMEM176B Antibody, FITC conjugated
    Biotin CSB-PA023758LD01HU TMEM176B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells.
  • 基因功能参考文献：
    1. Study characterized Tmem176a and b expression in RORgamma t+ lymphocytes at transcriptional and protein levels and present evidence that both genes exert a redundant ion channel function related to a colocalisation in close proximity to the Golgi apparatus. PMID: 27009467
    2. human TMEM176A and 176B protein levels are significantly elevated in lymphoma, but not in normal tissues PMID: 22244448
  • 亚细胞定位：
    Nucleus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    TMEM176 family
  • 组织特异性：
    Expressed in lung and dermal fibroblasts.
  • 数据库链接：

    HGNC: 29596

    OMIM: 610385

    KEGG: hsa:28959

    STRING: 9606.ENSP00000318409

    UniGene: Hs.647090