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TMEM131L Antibody

  • 中文名称：
    TMEM131L兔多克隆抗体
  • 货号：
    CSB-PA012218NA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of U251 cells with CSB-PA012218NA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TMEM131L Polyclonal antibody
  • Uniprot No.：
    A2VDJ0
  • 基因名：
    TMEM131L
  • 别名：
    TMEM131L antibody; KIAA0922 antibody; Transmembrane protein 131-like antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Peptide sequence from Human Transmembrane protein 131-like protein (963-978AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TMEM131L Antibody (CSB-PA012218NA01HU)，的标记方式是Non-conjugated。对于TMEM131L Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA012218NB01HU TMEM131L Antibody, HRP conjugated ELISA
    FITC CSB-PA012218NC01HU TMEM131L Antibody, FITC conjugated
    Biotin CSB-PA012218ND01HU TMEM131L Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation.
  • 基因功能参考文献：
    1. These results show that TMEM131L corresponds to an evolutionary conserved regulator of the Notch signaling pathway. PMID: 28347816
    2. these data indicate that, during thymopoiesis, stage-specific surface translocation of TMEM131L may regulate immature single-positive thymocyte proliferation arrest PMID: 23690469
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasm.; [Isoform 1]: Endoplasmic reticulum.; [Isoform 5]: Cytoplasm.
  • 蛋白家族：
    TMEM131 family
  • 组织特异性：
    Expressed in thymocytes.
  • 数据库链接：

    HGNC: 29146

    OMIM: 616243

    KEGG: hsa:23240

    STRING: 9606.ENSP00000386787

    UniGene: Hs.732450