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TMEM106A Antibody

  • 货号：
    CSB-PA023673LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of A2780 cells using CSB-PA023673LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TMEM106A Polyclonal antibody
  • Uniprot No.：
    Q96A25
  • 基因名：
    TMEM106A
  • 别名：
    TMEM106A; Transmembrane protein 106A
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 106A protein (1-94AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TMEM106A Antibody (CSB-PA023673LA01HU)，的标记方式是Non-conjugated。对于TMEM106A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023673LB01HU TMEM106A Antibody, HRP conjugated ELISA
    FITC CSB-PA023673LC01HU TMEM106A Antibody, FITC conjugated
    Biotin CSB-PA023673LD01HU TMEM106A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide. May play a role in inhibition of proliferation and migration.
  • 基因功能参考文献：
    1. Low TMEM106A expression is associated with gastric cancer. PMID: 24975047
  • 亚细胞定位：
    Cell membrane; Single-pass membrane protein.
  • 蛋白家族：
    TMEM106 family
  • 组织特异性：
    Expressed in renal cells (at protein level). Expressed in epithelial cells.
  • 数据库链接：

    HGNC: 28288

    KEGG: hsa:113277

    UniGene: Hs.536474