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TMED3 Antibody

  • 货号：
    CSB-PA897107LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TMED3 antibody at 6μg/ml + MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 25, 20 kDa
      Observed band size: 25 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA897107LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA897107LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TMED3 Polyclonal antibody
  • Uniprot No.：
    Q9Y3Q3
  • 基因名：
    TMED3
  • 别名：
    C15orf22 antibody; Integral type I protein antibody; Membrane protein p24B antibody; p24 family protein gamma 4 antibody; p24 family protein gamma-4 antibody; P24B antibody; p24g4 antibody; p24gamma4 antibody; p26 antibody; Testis tissue sperm binding protein Li 48e antibody; Tmed3 antibody; TMED3_HUMAN antibody; Transmembrane emp24 domain containing protein 3 antibody; Transmembrane emp24 domain-containing protein 3 antibody; Transmembrane p24 trafficking protein 3 antibody; UNQ5357/PRO1078 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transmembrane emp24 domain-containing protein 3 protein (24-180AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TMED3 Antibody (CSB-PA897107LA01HU)，的标记方式是Non-conjugated。对于TMED3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA897107LB01HU TMED3 Antibody, HRP conjugated ELISA
    FITC CSB-PA897107LC01HU TMED3 Antibody, FITC conjugated
    Biotin CSB-PA897107LD01HU TMED3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
  • 基因功能参考文献：
    1. Study demonstrates that transmembrane p24 trafficking protein 3 (TMED3) promotes hepatocellular carcinoma (HCC) metastasis and is a potential prognostic biomarker in hepatocellular carcinoma. Study propose that TMED3 promotes HCC metastasis through IL-11/STAT3 signaling. PMID: 27901021
    2. This genome-wide screen has identified two novel metastatic suppressors: TMED3 and SOX12, the knockdown of which increases metastatic growth after direct seeding. PMID: 24920608
  • 亚细胞定位：
    Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    EMP24/GP25L family
  • 数据库链接：

    HGNC: 28889

    KEGG: hsa:23423

    STRING: 9606.ENSP00000299705

    UniGene: Hs.513058