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TLE2 Antibody

  • 货号：
    CSB-PA050269
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q04725
  • 基因名：
    TLE2
  • 别名：
    enhancer of split groucho 2 antibody; enhancer of split groucho 2 antibody; Enhancer of split groucho-like protein 2 antibody; ESG antibody; ESG2 antibody; FLJ41188 antibody; GRG2 antibody; Groucho2 antibody; KIAA4188 antibody; MGC124808 antibody; mKIAA4188 antibody; Tle2 antibody; Tle2 protein antibody; TLE2_HUMAN antibody; transducin like enhancer of split 2 antibody; Transducin like enhancer of split 2, homolog of Drosophila E(sp1) antibody; Transducin like enhancer protein 2 antibody; Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) antibody; Transducin-like enhancer of split 2, homolog of Drosophila E(spl) antibody; Transducin-like enhancer protein 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human TLE2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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靶点详情

  • 功能：
    Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
  • 基因功能参考文献：
    1. Immunofluorescence analysis showed that TLE2 and RTA were colocalized in the same nuclear compartment in KSHV-infected cells. PMID: 19939918
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    WD repeat Groucho/TLE family
  • 组织特异性：
    In all tissues examined, mostly in heart, brain, and muscle.
  • 数据库链接：

    HGNC: 11838

    OMIM: 601041

    KEGG: hsa:7089

    STRING: 9606.ENSP00000262953

    UniGene: Hs.332173