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TIMM44 Antibody

  • 中文名称：
    TIMM44兔多克隆抗体
  • 货号：
    CSB-PA023555GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O43615
  • 基因名：
    TIMM44
  • 别名：
    TIMM44 antibody; MIMT44 antibody; TIM44 antibody; Mitochondrial import inner membrane translocase subunit TIM44 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TIMM44
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
  • 基因功能参考文献：
    1. TIM44 was identified for the first time as a potential oncogene, which plays an important role in autophagy through the TIM44-SOD2-ROS-mTOR pathway. PMID: 27849558
    2. The Timm44 gene may be a new target for the treatment of type 2 diabetes PMID: 25749183
    3. This protein has been found differentially expressed in thalami from patients with schizophrenia. PMID: 20471030
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Mitochondrion matrix.
  • 蛋白家族：
    Tim44 family
  • 数据库链接：

    HGNC: 17316

    OMIM: 605058

    KEGG: hsa:10469

    STRING: 9606.ENSP00000270538

    UniGene: Hs.465784