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THOC7 Antibody

  • 中文名称：
    THOC7兔多克隆抗体
  • 货号：
    CSB-PA023507GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q6I9Y2
  • 基因名：
    THOC7
  • 别名：
    FLJ23445 antibody; fSAP24 antibody; Functional spliceosome associated protein 24 antibody; Functional spliceosome-associated protein 24 antibody; hTREX30 antibody; Ngg1 interacting factor 3 like 1 binding protein 1 antibody; Ngg1 interacting factor 3 like protein 1 binding protein 1 antibody; Ngg1-interacting factor 3-like protein 1-binding protein 1 antibody; NIF3L1 binding protein 1 antibody; NIF3L1-binding protein 1 antibody; NIF3L1BP1 antibody; THO complex 7 homolog (Drosophila) antibody; THO complex 7 homolog antibody; THO complex subunit 7 homolog antibody; THOC 7 antibody; thoc7 antibody; THOC7_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human THOC7
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.; The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
  • 基因功能参考文献：
    1. THOC7 (50-137, amino acid numbers) binds to the N-terminal portion (1-199) of FMIP directly. PMID: 19059247
  • 亚细胞定位：
    Cytoplasm. Nucleus. Nucleus speckle.
  • 蛋白家族：
    THOC7 family
  • 数据库链接：

    HGNC: 29874

    OMIM: 611965

    KEGG: hsa:80145

    STRING: 9606.ENSP00000295899

    UniGene: Hs.288151