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TEF Antibody

  • 货号：
    CSB-PA004254
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of mouse brain cells using TEF Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q10587
  • 基因名：
    TEF
  • 别名：
    TEF antibody; KIAA1655 antibody; Thyrotroph embryonic factor antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human TEF.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription factor that binds to and transactivates the TSHB promoter. Binds to a minimal DNA-binding sequence 5'-[TC][AG][AG]TTA[TC][AG]-3'.
  • 基因功能参考文献：
    1. Resequencing three candidate genes (HOMER1, SLC6A4, and TEF) discovers seven potentially deleterious variants susceptibility to major depressive disorder and suicide attempts in Chinese. PMID: 27964944
    2. findings show the polymorphisms of Cry1 rs2287161 and Tef rs738499 are associated to major depressive disorder in the Chinese population PMID: 24581835
    3. The polymorphism of Tef rs738499 is associated with depression symptoms in parkinson disease. PMID: 23138696
    4. the TT genotype in Tef rs738499 is associated with sleep disturbances in Parkinson disease. PMID: 22257907
    5. evidence of TEF regulation through a miR-125b-mediated pathway PMID: 21347262
    6. TEF-expressing cells accumulated in G(0)/G(1) phase without undergoing apoptosis. PMID: 15665112

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    BZIP family, PAR subfamily
  • 数据库链接：

    HGNC: 11722

    OMIM: 188595

    KEGG: hsa:7008

    STRING: 9606.ENSP00000266304

    UniGene: Hs.181159