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TDRD9 Antibody

  • 货号：
    CSB-PA850866LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA850866LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TDRD9 Polyclonal antibody
  • Uniprot No.：
    Q8NDG6
  • 基因名：
    TDRD9
  • 别名：
    C14orf75 antibody; chromosome 14 open reading frame 75 antibody; DKFZp434N0820 antibody; FLJ36164 antibody; HIG 1 antibody; Hypoxia inducible HIG 1 antibody; MGC135025 antibody; NET54 antibody; Putative ATP dependent RNA helicase TDRD9 antibody; Putative ATP-dependent RNA helicase TDRD9 antibody; TDRD 9 antibody; Tdrd9 antibody; TDRD9_HUMAN antibody; Tudor domain containing 9 antibody; Tudor domain containing protein 9 antibody; Tudor domain-containing protein 9 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Putative ATP-dependent RNA helicase TDRD9 protein (286-585AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TDRD9 Antibody (CSB-PA850866LA01HU)，的标记方式是Non-conjugated。对于TDRD9 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA850866LB01HU TDRD9 Antibody, HRP conjugated ELISA
    FITC CSB-PA850866LC01HU TDRD9 Antibody, FITC conjugated
    Biotin CSB-PA850866LD01HU TDRD9 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    ATP-binding RNA helicase required during spermatogenesis. Required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effector in the nucleus together with PIWIL4.
  • 基因功能参考文献：
    1. first report of a recessive deleterious mutation in TDRD9 in humans; study demonstrates that non-obstructive azoospermia can be caused by a mutation in TDRD9 PMID: 28536242
  • 相关疾病：
    Defects in TDRD9 may be a cause of non-obstructive azoospermia, a disorder characterized by the absence of sperm. Female fertility is not affected.
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    DEAD box helicase family, DEAH subfamily
  • 数据库链接：

    HGNC: 20122

    KEGG: hsa:122402

    STRING: 9606.ENSP00000387303

    UniGene: Hs.21454