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TBPL2 Antibody

  • 货号：
    CSB-PA264692
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from HeLa cells, using TBPL2 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TBPL2 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TBPL2 Polyclonal antibody
  • Uniprot No.：
    Q6SJ96
  • 基因名：
    TBPL2
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from internal of Human TBPL2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
  • 基因功能参考文献：
    1. study indicates that the TBP2 gene is not responsible for idiopathic primary ovarian insufficiency in the Chinese Han population PMID: 27642674
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    3. TRF3 is a nuclear protein that is present in all human and mouse tissues and cell lines examined PMID: 14634207
    4. Here we report that differentiation of myoblast to myotubes involves the disruption of the canonical holo-TFIID and replacement by a novel TRF3/TAF3 (TBP-related factor 3/TATA-binding protein-associated factor 3) complex. PMID: 17704303
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    TBP family
  • 组织特异性：
    Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.
  • 数据库链接：

    HGNC: 19841

    OMIM: 608964

    KEGG: hsa:387332

    STRING: 9606.ENSP00000247219

    UniGene: Hs.528278