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TARS Antibody

  • 货号：
    CSB-PA023131ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TARS antibody at 4.85µg/ml
      Lane 1: A549 whole cell lysate
      Lane 2: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 84, 87 kDa
      Observed band size: 84 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023131ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA023131ESR2HU at dilution of 1:100
    • Immunoprecipitating TARS in A549 whole cell lysate
      Lane 1: Rabbit control IgG instead of CSB-PA023131ESR2HU in A549 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA023131ESR2HU (8µg) + A549 whole cell lysate (500µg)
      Lane 3: A549 whole cell lysate (10µg)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TARS Polyclonal antibody
  • Uniprot No.：
    P26639
  • 基因名：
    TARS
  • 别名：
    cytoplasmic antibody; MGC9344 antibody; SYTC_HUMAN antibody; TARS antibody; Threonine tRNA ligase 1 antibody; Threonine tRNA ligase 1; cytoplasmic antibody; Threonine--tRNA ligase antibody; Threonyl tRNA synthetase antibody; Threonyl tRNA synthetase; cytoplasmic antibody; Threonyl-tRNA synthetase antibody; ThrRS antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Threonine--tRNA ligase, cytoplasmic protein (1-230AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IP
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage.
  • 基因功能参考文献：
    1. Results show that TARS expression is increased in epithelial ovarian cancer. PMID: 25163878
    2. Our series mainly underscores that interstitial lung disease is frequent in anti-PL7(tars antibody)patients, leading to high morbidity. PMID: 23375620
    3. A previously undiscovered function for TARS as an angiogenic, pro-migratory extracellular signaling molecule. PMID: 23425968
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class-II aminoacyl-tRNA synthetase family
  • 数据库链接：

    HGNC: 11572

    OMIM: 187790

    KEGG: hsa:6897

    STRING: 9606.ENSP00000265112

    UniGene: Hs.481860