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TAF3 Antibody

  • 货号：
    CSB-PA564583
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from K562 cells, using TAF3 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TAF3 Polyclonal antibody
  • Uniprot No.：
    Q5VWG9
  • 基因名：
    TAF3
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human TAF3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
  • 基因功能参考文献：
    1. Data show that transcription cofactor TAF3 is required for transcription of the alpha spectrin SPTA1 gene. PMID: 23935956
    2. Study shows that H3K4me3-TAF3 interactions direct global TFIID recruitment to active genes, some of which are p53 targets. Further analyses show that H3K4me3 enhances p53-dependent transcription by stimulating preinitiation complex formation. PMID: 23452851
    3. Study shows that this TAF3 activity is critical for early lineage segregation during stem cell differentiation. PMID: 21884934
    4. Data identified TAF3 as an evolutionarily conserved negative regulator of p53 transcription activation function. PMID: 18549481
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    TAF3 family
  • 数据库链接：

    HGNC: 17303

    OMIM: 606576

    KEGG: hsa:83860

    STRING: 9606.ENSP00000340271

    UniGene: Hs.527688