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SUPT3H Antibody

  • 货号：
    CSB-PA022956LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: SUPT3H antibody at 2µg/ml
      Lane 1: Mouse brain tissue
      Lane 2: Colo320 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 36, 38 kDa
      Observed band size: 36 kDa
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA022956LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA022956LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SUPT3H Polyclonal antibody
  • Uniprot No.：
    O75486
  • 基因名：
    SUPT3H
  • 别名：
    SUPT3H antibody; SPT3 antibody; Transcription initiation protein SPT3 homolog antibody; SPT3-like protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Transcription initiation protein SPT3 homolog protein (1-328AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SUPT3H Antibody (CSB-PA022956LA01HU)，的标记方式是Non-conjugated。对于SUPT3H Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA022956LB01HU SUPT3H Antibody, HRP conjugated ELISA
    FITC CSB-PA022956LC01HU SUPT3H Antibody, FITC conjugated
    Biotin CSB-PA022956LD01HU SUPT3H Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable transcriptional activator.
  • 基因功能参考文献：
    1. significance of the formation PVT1- SUPT3H chimeric gene remains unknown and the overexpression of MYC by ectopic promoter on chromosome 6 may be essential to tumor genesis. PMID: 25860292
    2. we identified rs41314453 as the main genetic determinant of ADAMTS13 activity, and we present preliminary findings for further associations at the ADAMTS13 and SUPT3H loci. PMID: 25934476
    3. identified a significant excess of genes with pivotal roles in bone homeostasis, such as PPPT3B and the height associated SUPT3H-RUNX2 PMID: 22407027
    4. suggest a novel STAF65gamma-dependent function of STAGA-type complexes in cell proliferation and transcription activation by MYC postloading of TFIID and RNA polymerase II that involves direct recruitment of core Mediator PMID: 17967894
    5. Found evidence of Mendelian Transmission Distortion in the region harboring SUPT3H in one HapMap population. PMID: 19259136

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    SPT3 family
  • 组织特异性：
    Expressed in all tissues tested including pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.
  • 数据库链接：

    HGNC: 11466

    OMIM: 602947

    STRING: 9606.ENSP00000360515

    UniGene: Hs.368325