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SULT1C2 Antibody

  • 货号：
    CSB-PA022938ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA022938ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA022938ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SULT1C2 Polyclonal antibody
  • Uniprot No.：
    O00338
  • 基因名：
    SULT1C2
  • 别名：
    humSULTC2 antibody; ST1C1 antibody; ST1C2 antibody; ST1C2_HUMAN antibody; Sulfotransferase 1C1 antibody; Sulfotransferase 1C2 antibody; Sulfotransferase family cytosolic 1C member 1 antibody; Sulfotransferase family cytosolic 1C member 2 antibody; SULT1C#1 antibody; SULT1C1 antibody; SULT1C2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Sulfotransferase 1C2 protein (1-120AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Sulfonates p-nitrophenol, a small phenolic compond. Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol. Catalyzes the sulfonation of the carcinogenic N-Hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis.
  • 基因功能参考文献：
    1. Vitamin D receptor can interact directly with the SULT1C2 VDRE sequence to transcriptionally regulation SULT1C2 expression in colorectal tumor cells. PMID: 27130351
    2. Our findings are the first to characterize the regulation of human SULT1C2 and SULT1C3 expression by several transcription factor activators. PMID: 24335393
    3. gene resequencing and functional genomic studies PMID: 11740338
    4. crystal structures of two members of SULT1 family, SULT1B1 and SULT1C1, both in complex with the product of the PAPS cofactor, adenosine-3-5-diphosphate (PAP). PMID: 16804942
  • 亚细胞定位：
    Cytoplasm. Lysosome.
  • 蛋白家族：
    Sulfotransferase 1 family
  • 组织特异性：
    Found in adult stomach, kidney and thyroid gland, and in fetal kidney and liver.
  • 数据库链接：

    HGNC: 11456

    OMIM: 602385

    KEGG: hsa:6819

    UniGene: Hs.436123