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SULT1B1 Antibody

  • 货号：
    CSB-PA209693
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA209693(SULT1B1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA209693(SULT1B1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal intestines tissue, Primary antibody: CSB-PA209693(SULT1B1 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds
  • 其他：

产品详情

  • Uniprot No.：
    O43704
  • 基因名：
    SULT1B1
  • 别名：
    Dopa/tyrosine sulfotransferase antibody; MGC13356 antibody; ST1B1 antibody; ST1B1_HUMAN antibody; ST1B2 antibody; Sulfotransferase 1B1 antibody; Sulfotransferase 1B2 antibody; Sulfotransferase family 1B member 1 antibody; Sulfotransferase family cytosolic 1B member 1 antibody; SULT1B1 antibody; SULT1B2 antibody; Thyroid hormone sulfotransferase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Fusion protein of Human SULT1B1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3).
  • 基因功能参考文献：
    1. (L145V) selectively expressed in African descendants exhibits altered kinetic properties PMID: 28084139
    2. the intersubunit interactions of SULT1B1 as it relates to enzyme activity PMID: 27338799
    3. linkage to SULT1E1 and a SULT1D1 pseudogene on chromosome 4 PMID: 11688987
    4. crystal structures of two members of SULT1 family, SULT1B1 and SULT1C1, both in complex with the product of the PAPS cofactor, adenosine-3-5-diphosphate (PAP). PMID: 16804942
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Sulfotransferase 1 family
  • 组织特异性：
    Highly expressed in the liver, peripheral blood leukocytes, colon (mucosal lining), small intestine (jejunum) and spleen. A lesser expression was observed in the lung, placenta and thymus.
  • 数据库链接：

    HGNC: 17845

    OMIM: 608436

    KEGG: hsa:27284

    UniGene: Hs.129742