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STXBP6 Antibody

  • 货号：
    CSB-PA850881LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: STXBP6 antibody at 2μg/ml + Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit at 1/10000 dilution
      Predicted band size: 24, 12 kDa
      Observed band size: 24 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA850881LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA850881LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA850881LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) STXBP6 Polyclonal antibody
  • Uniprot No.：
    Q8NFX7
  • 基因名：
    STXBP6
  • 别名：
    Amisyn antibody; FLJ39638 antibody; HSPC156 antibody; STXB6_HUMAN antibody; STXBP6 antibody; syntaxin binding protein 6 (amisyn) antibody; Syntaxin binding protein 6 antibody; Syntaxin-binding protein 6 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Syntaxin-binding protein 6 protein (2-210AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，STXBP6 Antibody (CSB-PA850881LA01HU)，的标记方式是Non-conjugated。对于STXBP6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA850881LB01HU STXBP6 Antibody, HRP conjugated ELISA
    FITC CSB-PA850881LC01HU STXBP6 Antibody, FITC conjugated
    Biotin CSB-PA850881LD01HU STXBP6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.
  • 基因功能参考文献：
    1. Our results provide a basis for the genetic etiology of lung adenocarcinoma by demonstrating the possible role of hypermethylation of STXBP6 in poor clinical outcomes in lung cancer patients. PMID: 28198450
    2. Data suggest that genetic variations within CD6 and syntaxin binding protein 6 (STXBP6) may influence response to TNFalpha inhibitors in patients with rheumatoid arthritis (RA). PMID: 22685579
  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 组织特异性：
    Detected at low levels in brain, and at very low levels in heart, adrenal gland, testis, liver and kidney.
  • 数据库链接：

    HGNC: 19666

    OMIM: 607958

    KEGG: hsa:29091

    STRING: 9606.ENSP00000324302

    UniGene: Hs.508958