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  4. STRA8 Antibody

STRA8 Antibody

  • 货号：
    CSB-PA185143
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA185143(STRA8 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA185143(STRA8 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q7Z7C7
  • 基因名：
    STRA8
  • 别名：
    Stimulated by retinoic acid 8 antibody; stimulated by retinoic acid 8 homolog antibody; Stimulated by retinoic acid Gene 8 antibody; stimulated by retinoic acid gene 8 homolog antibody; Stimulated by retinoic acid gene 8 protein homolog antibody; STRA 8 antibody; STRA8 antibody; STRA8_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide of Human STRA8
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
  • 基因功能参考文献：
    1. The genetic variant rs10269148 of STRA8 gene shows higher risk of spermatogenic impairment in the groups of abnormospermia than the controls PMID: 23320086
    2. Functional characterization of an homologous mouse gene. PMID: 18799751
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
    4. Expression restricted to testis (STRA8) PMID: 12489526
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Expressed specifically in testis and fetal ovaries.
  • 数据库链接：

    HGNC: 30653

    OMIM: 609987

    KEGG: hsa:346673

    STRING: 9606.ENSP00000275764

    UniGene: Hs.592279