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STK35 Antibody

  • 货号：
    CSB-PA036719
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA036719(STK35 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q8TDR2
  • 基因名：
    STK35
  • 别名：
    CLIK-1 antibody; Clik1 antibody; CLP 36 interacting kinase antibody; CLP-36-interacting kinase 1 antibody; EC 2.7.1.37 antibody; PDLIM1 interacting kinase antibody; PDLIM1-interacting kinase 1 antibody; Serine threonine kinase 35 long form antibody; Serine/threonine kinase 35 antibody; Serine/threonine protein kinase 35 antibody; Serine/threonine-protein kinase 35 antibody; Serine/threonine-protein kinase 35 L1 antibody; STK35 antibody; STK35_HUMAN antibody; STK35L1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human STK35
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:30-1:150
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. STK35 knockdown enhanced apoptosis. Expression of the active forms and the activity of two major executioner caspases, caspase 3 and caspase 7, were also increased in osteosarcoma cells with STK35 silenced. PMID: 29414823
    2. constitutive overexpression of STK35 proteins enhances caspase-independent cell death under oxidative stress conditions. PMID: 21964068
    3. by regulating CDKN2A and inhibiting G1- to S-phase transition STK35L1 may act as a central kinase linking the cell cycle and migration of endothelial cells PMID: 21283756
    4. analysis of the STK35L proteins in human and in sea squirts PMID: 19756140
    5. results establish the CLP-36 PDZ-LIM protein as an adapter, recruiting the Clik1 kinase to actin stress fibers in nonmuscle cells, and suggest that Clik1 represents a novel regulator of actin stress fibers PMID: 11973348

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  • 亚细胞定位：
    Nucleus. Nucleus, nucleolus. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 组织特异性：
    Expressed in testis.
  • 数据库链接：

    HGNC: 16254

    OMIM: 609370

    KEGG: hsa:140901

    STRING: 9606.ENSP00000370891

    UniGene: Hs.100057