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STK16 Antibody

  • 货号：
    CSB-PA041746
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA041746(STK16 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    O75716
  • 基因名：
    STK16
  • 别名：
    EDPK antibody; F52 antibody; FLJ39635 antibody; hPSK antibody; KRCT antibody; MGC16211 antibody; MPSK antibody; MPSK1 antibody; Myristoylated and palmitoylated serine/threonine protein kinase antibody; Myristoylated and palmitoylated serine/threonine-protein kinase antibody; PKL12 antibody; Protein kinase expressed in day 12 fetal liver antibody; Protein kinase Krct antibody; Protein kinase PKL12 antibody; Serine/threonine kinase 16 antibody; Serine/threonine protein kinase 16 antibody; Serine/threonine-protein kinase 16 antibody; Stk16 antibody; STK16_HUMAN antibody; TGF beta stimulated factor 1 antibody; TGF-beta-stimulated factor 1 antibody; TGFB stimulated factor 1 antibody; Transforming growth factor beta stimulated factor 1 antibody; TSF-1 antibody; TSF1 antibody; Tyrosine protein kinase STK16 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human STK16
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:20-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
  • 基因功能参考文献：
    1. we revealed STK16 as a novel actin binding protein that resides in the Golgi, which regulates actin dynamics to control Golgi structure and participate in cell cycle progression. PMID: 28294156
    2. MAL2 and STK16 function to sort secretory soluble cargo into the constitutive secretory pathway in hepatocytes. PMID: 25084525
    3. The Endogenous STK16 subcellular localization was evaluated by indirect immunofluorescence in NRK cells, demonstrating a Golgi-associated pattern that appears to be independent of signals provided by integrin pathways. PMID: 16310770
  • 亚细胞定位：
    Cytoplasm, perinuclear region. Membrane; Lipid-anchor.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 组织特异性：
    Ubiquitously expressed at very low levels.
  • 数据库链接：

    HGNC: 11394

    OMIM: 604719

    KEGG: hsa:8576

    STRING: 9606.ENSP00000379964

    UniGene: Hs.153003