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SSFA2 Antibody

  • 货号：
    CSB-PA022710GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P28290
  • 基因名：
    SSFA2
  • 别名：
    Cleavage signal-1 protein antibody; CS-1 antibody; CS1 antibody; Ki-ras-induced actin-interacting protein antibody; KIAA1927 antibody; KRAP antibody; KRAS induced actin interacting protein antibody; SPAG13 antibody; Sperm associated antigen 13 antibody; Sperm-specific antigen 2 antibody; SSFA2 antibody; SSFA2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SSFA2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. phosphorylation at Ser92 of the sperm-specific antigen 2 (SSFA2)[phospho-SSFA2 (pS92)], was related to poor prognosis. PMID: 26947549
    2. the predicted coiled-coil region & the region adjacent to the coiled-coil region of the carboxyl-terminus of KRAP may be crucial for its interaction with the cytoskeleton or directional targeting toward the apical pole in polarized epithelial cells PMID: 21873152
    3. KRAP is involved in the proper regulation of IP3R-mediated Ca2+ release. PMID: 21457704
    4. the critical region of KRAP protein for the regulation of IP(3)R was determined. PMID: 21501587
    5. localized as a membrane-bound form with extracellular regions; results suggested KRAP might be involved in the regulation of filamentous actin and signals from the outside of the cells PMID: 14673706
    6. results suggested that KRAP might be a cytoskeleton-associated protein involving the structural integrity and/or signal transductions in human cancers. PMID: 17934691

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  • 亚细胞定位：
    Cytoplasm. Note=Located near the plasma membrane. Associated with actin filaments. May also exist as a membrane-bound form with extracellular regions.
  • 组织特异性：
    Strongly expressed in pancreas and testis. Present in colon cancer cells (at protein level).
  • 数据库链接：

    HGNC: 11319

    OMIM: 118990

    KEGG: hsa:6744

    STRING: 9606.ENSP00000388731

    UniGene: Hs.196983