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SPTBN5 Antibody

  • 货号：
    CSB-PA020284
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9NRC6
  • 基因名：
    SPTBN5
  • 别名：
    Beta-V spectrin antibody; brain 4 antibody; BSPECV antibody; HUBSPECV antibody; HUSPECV antibody; non-erythroid beta chain 4 antibody; Spectrin antibody; Spectrin beta chain antibody; Spectrin beta chain, brain 4 antibody; Spectrin, non-erythroid beta chain 4 antibody; SPTBN4 antibody; SPTBN5 antibody; SPTN5_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Spectrin β V.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    IHC 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Adaptive mutations of spectrin-betaV occurred in the mammalian lineage and were accompanied with substantial changes in the protein distribution within inner ear hair cells. PMID: 28179572
    2. study identified spectrin betaV as a myosin VIIa- and rhodopsin-interacting partner in photoreceptor cells; suggest that spectrin betaV homomers couple some USH1 proteins, opsin and other phototransduction proteins to both actin- and microtubule-based motors, thereby contributing to their transport towards the photoreceptor outer disks PMID: 23704327
    3. interaction of hTRPC4 with alphaII-spectrin and betaV-spectrin was confirmed by glutathione S-transferase pulldown and co-immunoprecipitation experiments PMID: 18048348
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Note=Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.
  • 蛋白家族：
    Spectrin family
  • 组织特异性：
    Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.
  • 数据库链接：

    HGNC: 15680

    OMIM: 605916

    KEGG: hsa:51332

    STRING: 9606.ENSP00000317790

    UniGene: Hs.709819