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SPCS1 Antibody

  • 货号：
    CSB-PA896543LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA896543LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SPCS1 Polyclonal antibody
  • Uniprot No.：
    Q9Y6A9
  • 基因名：
    SPCS1
  • 别名：
    HSPC033 antibody; Microsomal signal peptidase 12 kDa subunit antibody; OTTHUMP00000206959 antibody; signal peptidase 12kDa antibody; Signal peptidase complex subunit 1 antibody; signal peptidase complex subunit 1 homolog (S. cerevisiae) antibody; SPase 12 kDa subunit antibody; SPC1 antibody; SPC12 antibody; SPCS1 antibody; SPCS1_HUMAN antibody; YJR010C-A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Signal peptidase complex subunit 1 protein (70-102AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SPCS1 Antibody (CSB-PA896543LA01HU)，的标记方式是Non-conjugated。对于SPCS1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA896543LB01HU SPCS1 Antibody, HRP conjugated ELISA
    FITC CSB-PA896543LC01HU SPCS1 Antibody, FITC conjugated
    Biotin CSB-PA896543LD01HU SPCS1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.; (Microbial infection) Required for the post-translational processing of proteins involved in virion assembly and secretion from flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), Dengue virus type 2 (DENV-2), Yellow Fever virus (YFV), Zika virus (ZIKV) and hepatitis C virus (HCV). Plays a key role in the post-translational processing of flaviviral structural proteins prM, E, and NS1. In HCV, it is involved in virion assembly where it promotes the interaction between HCV virus proteins NS2 and E2.
  • 基因功能参考文献：
    1. the results demonstrate that SPCS1 affects viral replication by interacting with NS2B, thereby influencing the posttranslational processing of Japanese Encephalitis Virus proteins and the assembly of virions. PMID: 29593046
    2. SPCS1 plays a key role in the formation of the membrane-associated NS2-E2 complex via its interaction with NS2 and E2, which leads to a coordinating interaction between the structural and non-structural proteins PMID: 24009510
  • 亚细胞定位：
    Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SPCS1 family
  • 数据库链接：

    HGNC: 23401

    OMIM: 610358

    KEGG: hsa:28972

    STRING: 9606.ENSP00000233025

    UniGene: Hs.11125