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SNUPN Antibody

  • 中文名称：
    SNUPN兔多克隆抗体
  • 货号：
    CSB-PA022350GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O95149
  • 基因名：
    SNUPN
  • 别名：
    0610031A09Rik antibody; KPNBL antibody; MGC134006 antibody; MGC95000 antibody; RNA U transporter 1 antibody; RNA, U transporter 1 antibody; RNUT 1 antibody; RNUT1 antibody; SNUPN antibody; Snupn1 antibody; Snurportin 1 antibody; Snurportin-1 antibody; Snurportin1 antibody; SPN1 antibody; SPN1_HUMAN antibody; wu:fc41a03 antibody; zgc:77819 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SNUPN
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
  • 基因功能参考文献：
    1. Results show that marker rs218966 in gene PHF14 and rs9836027 in MAP4 significantly associated with hypertension; additionally, rare variants in SNUPN significantly associated with systolic blood pressure. PMID: 26866982
    2. analysis of interactions between CRM1 and the nuclear pore protein Tpr and snurportin PMID: 24722547
    3. SPN construct lacking the importin beta binding domain (IBB) localizes primarily to the nucleus rather than to the cytoplasm. PMID: 12095920
    4. There is an interaction between the N- and C-terminal domains of SPN, suggesting an autoregulatory function similar to that of importin-alpha. PMID: 16030253
    5. study presents the crystal structure of the SPN1.CRM1.RanGTP export complex at 2.5 angstrom resolution (where SPN1 is snurportin1 and RanGTP is guanosine 5' triphosphate-bound Ran PMID: 19389996
    6. the binding of dimethylated RNA-caps to snurportin 1 PMID: 19619473

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  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Snurportin family
  • 数据库链接：

    HGNC: 14245

    OMIM: 607902

    KEGG: hsa:10073

    STRING: 9606.ENSP00000309831

    UniGene: Hs.21577