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SNPH Antibody

  • 货号：
    CSB-PA022317GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O15079
  • 基因名：
    SNPH
  • 别名：
    bA314N13.5 antibody; KIAA0374 antibody; Snph antibody; SNPH_HUMAN antibody; Syntaphilin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SNPH
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibits SNARE complex formation by absorbing free syntaxin-1.
  • 基因功能参考文献：
    1. SNPH is a stress-regulated mitochondrial switch of the cell proliferation-motility balance in cancer, and its pathway may represent a therapeutic target. PMID: 28891816
    2. Stressed mitochondria are removed from axons triggered by the bulk release of mitochondrial anchoring protein syntaphilin via a new class of mitochondria-derived cargos independent of Parkin, Drp1, and autophagy. PMID: 28472658
    3. syntaphilin is an inhibitor of both SNARE-based fusion and dynamin-mediated endocytosis PMID: 12896979
  • 亚细胞定位：
    Membrane; Single-pass membrane protein. Cell junction, synapse, synaptosome.
  • 组织特异性：
    Brain specific. Found in synapses.
  • 数据库链接：

    HGNC: 15931

    OMIM: 604942

    KEGG: hsa:9751

    STRING: 9606.ENSP00000371297

    UniGene: Hs.323833