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SMNDC1 Antibody

  • 货号：
    CSB-PA021840GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O75940
  • 基因名：
    SMNDC1
  • 别名：
    30 kDa splicing factor SMNrp antibody; MGC106917 antibody; MGC112663 antibody; SMN related protein antibody; SMN-related protein antibody; smndc1 antibody; SMNR antibody; SPF30 antibody; SPF30_HUMAN antibody; Splicing factor 30, survival of motor neuron-related antibody; Survival motor neuron domain containing 1 antibody; Survival motor neuron domain containing protein 1 antibody; Survival motor neuron domain-containing protein 1 antibody; Survival of motor neuron related splicing factor 30 antibody; Survival of motor neuron-related-splicing factor 30 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SMNDC1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in spliceosome assembly.
  • 基因功能参考文献：
    1. The results show that SMNDC1 mRNA 5'-UTR forms an intramolecular, parallel G quadruplex structure comprised of three G quartet planes, which is bound specifically by FMRP both in vitro and in mouse brain lysates. PMID: 28612854
    2. The binding specificity and affinity of the Tudor domains of TDRD3, SMN and SPF30 proteins were characterized quantitatively. PMID: 22363433
    3. The structures of SMN and SPF30 Tudor domains bound to symmetric and asymmetric dimethylated arginine (DMA) are presented. PMID: 22101937
    4. U2AF35 and hPrp3 interactions with SPF30 can occur simultaneously, thereby potentially linking 3' splice site recognition with tri-small nuclear ribonucleoprotein addition PMID: 18211889
  • 亚细胞定位：
    Nucleus speckle. Nucleus, Cajal body.
  • 蛋白家族：
    SMN family
  • 组织特异性：
    Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.
  • 数据库链接：

    HGNC: 16900

    OMIM: 603519

    KEGG: hsa:10285

    STRING: 9606.ENSP00000358605

    UniGene: Hs.632093