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SLC7A3 Antibody

  • 货号：
    CSB-PA855505LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA855505LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC7A3 Polyclonal antibody
  • Uniprot No.：
    Q8WY07
  • 基因名：
    SLC7A3
  • 别名：
    SLC7A3 antibody; ATRC3 antibody; CAT3 antibody; Cationic amino acid transporter 3 antibody; CAT-3 antibody; CAT3 antibody; Cationic amino acid transporter y+ antibody; Solute carrier family 7 member 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Cationic amino acid transporter 3 protein (428-475AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC7A3 Antibody (CSB-PA855505LA01HU)，的标记方式是Non-conjugated。对于SLC7A3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA855505LB01HU SLC7A3 Antibody, HRP conjugated ELISA
    FITC CSB-PA855505LC01HU SLC7A3 Antibody, FITC conjugated
    Biotin CSB-PA855505LD01HU SLC7A3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.
  • 基因功能参考文献：
    1. rare hypomorphic variants of SLC7A3 exist in male individuals, SLC7A3 variants possibly contribute to the etiology of autism spectrum disorders in male subjects in association with other genetic factors PMID: 26215737
    2. knockdown impaired AMPK-PPAR-alpha signaling and resulted in lipid accumulation under glucose starvation in liver cells PMID: 25130427
    3. CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution. PMID: 22870827
    4. is concluded that hCAT-3 is a passive transport system that conducts monovalent cations including L-Arg. PMID: 15737334
    5. It is concluded that similar to hCAT-1, hCAT-3 activity is decreased by PKC via reduction of transporter molecules in the plasma membrane. PMID: 16332251

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Amino acid-polyamine-organocation (APC) superfamily, Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
  • 组织特异性：
    Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala.
  • 数据库链接：

    HGNC: 11061

    OMIM: 300443

    KEGG: hsa:84889

    STRING: 9606.ENSP00000298085

    UniGene: Hs.175220