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SLC4A8 Antibody

  • 货号：
    CSB-PA649721LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: SLC4A8 antibody at 2µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 123, 121, 118, 112, 78, 84, 72 kDa
      Observed band size: 123 kDa
    • Immunohistochemistry of paraffin-embedded human salivary gland tissue using CSB-PA649721LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA649721LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA649721LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC4A8 Polyclonal antibody
  • Uniprot No.：
    Q2Y0W8
  • 基因名：
    SLC4A8
  • 别名：
    Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody; Electroneutral sodium bicarbonate exchanger 1 antibody; k-NBC3 antibody; S4A8_HUMAN antibody; Slc4a8 antibody; SLC4A8 protein antibody; Solute carrier family 4 member 8 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Electroneutral sodium bicarbonate exchanger 1 protein (1-300AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC4A8 Antibody (CSB-PA649721LA01HU)，的标记方式是Non-conjugated。对于SLC4A8 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA649721LB01HU SLC4A8 Antibody, HRP conjugated ELISA
    FITC CSB-PA649721LC01HU SLC4A8 Antibody, FITC conjugated
    Biotin CSB-PA649721LD01HU SLC4A8 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
  • 基因功能参考文献：
    1. This study confirmed the presence in human cDNA of mouse NDCBE-like transcripts (human NDCBE-A) and three novel transcripts NDCBE-C, NDCBE-D, and NDCBE-D'. PMID: 18577713
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Anion exchanger (TC 2.A.31) family
  • 组织特异性：
    Expressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed i
  • 数据库链接：

    HGNC: 11034

    OMIM: 605024

    KEGG: hsa:9498

    STRING: 9606.ENSP00000405812

    UniGene: Hs.4749