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SLC35B4 Antibody

  • 货号：
    CSB-PA853373LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of A2780 cells using CSB-PA853373LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC35B4 Polyclonal antibody
  • Uniprot No.：
    Q969S0
  • 基因名：
    SLC35B4
  • 别名：
    SLC35B4 antibody; YEA4 antibody; PSEC0055 antibody; UDP-xylose and UDP-N-acetylglucosamine transporter antibody; Solute carrier family 35 member B4 antibody; YEA4 homolog antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human UDP-xylose and UDP-N-acetylglucosamine transporter protein (174-200AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC35B4 Antibody (CSB-PA853373LA01HU)，的标记方式是Non-conjugated。对于SLC35B4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA853373LB01HU SLC35B4 Antibody, HRP conjugated ELISA
    FITC CSB-PA853373LC01HU SLC35B4 Antibody, FITC conjugated
    Biotin CSB-PA853373LD01HU SLC35B4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
  • 基因功能参考文献：
    1. Glucose levels activate SLC35B4 expression. This triggers a downstream effect via Hsp60 and other proteins. We hypothesize that the downstream effect on the proteins is mediated via altering the glycosylation pattern inside liver cells PMID: 29867058
    2. subcellular localization of SLC35B4 PMID: 21918738
    3. Decreased SLC35B4 expression led to increased gluconeogenesis in HepG2 cells. PMID: 21507882
    4. Transport capabilities for UDP-Glc and UDP-Xyl were determined with Golgi vesicles isolated from transformed cells PMID: 15911612
  • 亚细胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Nucleotide-sugar transporter family, SLC35B subfamily
  • 数据库链接：

    HGNC: 20584

    OMIM: 610923

    KEGG: hsa:84912

    STRING: 9606.ENSP00000367770

    UniGene: Hs.490181