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SLC35A2 Antibody

  • 货号:
    CSB-PA021584LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Western Blot
      Positive WB detected in: 293 whole cell lysate, PC-3 whole cell lysate, MCF7 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, HepG2 whole cell lysate, SH-SY5Y whole cell lysate, Mouse Heart tissue lysate, Mouse Brain tissue lysate, Mouse Kidney tissue lysate, Mouse Liver tissue lysate, Rat Brain tissue lysate, Rat Stomach tissue lysate, Rat Kidney tissue lysate
      All lanes:SLC35A2 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 41kDa
      Observed band size: 41 kDa
    • IHC image of CSB-PA021584LA01HU diluted at 1:150 and staining in paraffin-embedded human prostate.cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) SLC35A2 Polyclonal antibody
  • Uniprot No.:
    P78381
  • 基因名:
    SLC35A2
  • 别名:
    SLC35A2 antibody; UGALT antibody; UGT antibody; UGTL antibody; UDP-galactose translocator antibody; Solute carrier family 35 member A2 antibody; UDP-galactose transporter antibody; UDP-Gal-Tr antibody; UGT antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human, Mouse
  • 免疫原:
    Recombinant Human UDP-galactose translocator protein (136-234AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,SLC35A2 Antibody (CSB-PA021584LA01HU),的标记方式是Non-conjugated。对于SLC35A2 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA021584LB01HU SLC35A2 Antibody, HRP conjugated ELISA
    FITC CSB-PA021584LC01HU SLC35A2 Antibody, FITC conjugated
    Biotin CSB-PA021584LD01HU SLC35A2 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, WB, IF
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1:2000-1:5000
    IF 1:50-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
  • 基因功能参考文献:
    1. The short N-terminal region composed of 35 N-terminal amino-acid residues of UGT was crucial for galactosylation of N-glycans. PMID: 25451267
    2. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
    3. De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy. PMID: 24115232
    4. The data further supports the hypothesis that UGT and NGT cooperate in the UDP-Gal delivery for glycosyltransferases located in the Golgi apparatus. PMID: 23583405
    5. Mosaicism of the UDP-galactose transporter SLC35A2 causes a congenital disorder of glycosylation. PMID: 23561849
    6. localization of the UDP-Gal transporter may depend on the presence of the partner splice variant PMID: 21918738

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  • 相关疾病:
    Congenital disorder of glycosylation 2M (CDG2M)
  • 亚细胞定位:
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Nucleotide-sugar transporter family, SLC35A subfamily
  • 数据库链接:

    HGNC: 11022

    OMIM: 300896

    KEGG: hsa:7355

    STRING: 9606.ENSP00000247138

    UniGene: Hs.21899