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SLC32A1 Antibody

  • 货号：
    CSB-PA863984LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse brain tissue
      All lanes: SLC32A1 antibody at 3.4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 58 kDa
      Observed band size: 58 kDa
    • Immunohistochemistry of paraffin-embedded human eye tissue using CSB-PA863984LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA863984LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：

    The SLC32A1 antibody can be used to recognize the human and mouse SLC32A1 protein. When a rabbit received an injection of the recombinant human SLC32A1 protein (14-118aa), an immune response occurred in the rabbit producing large amounts of antibodies against the SLC32A1 protein. The rabbit's blood was collected and isolated to get the anti-serum, which was subjected to protein G purification to obtain the SLC32A1 polyclonal antibody (purity 95%+). This SLC32A1 antibody has accessed its specificity in ELISA, WB, IHC, and IF applications.

    SLC32A1, also known as VIAAT, is a membrane protein responsible for transporting inhibitory neurotransmitters, such as gamma-aminobutyric acid (GABA) and glycine, into synaptic vesicles in neurons. It plays an important role in the regulation of neuronal excitability and inhibition in the nervous system. Dysfunction of SLC32A1 has been associated with several neurological and psychiatric disorders, including epilepsy, schizophrenia, and autism.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC32A1 Polyclonal antibody
  • Uniprot No.：
    Q9H598
  • 基因名：
  • 别名：
    bA122O1.1 antibody; GABA and glycine transporter antibody; hVIAAT antibody; SLC32A 1 antibody; Slc32a1 antibody; solute carrier family 32 (GABA vesicular transporter) member 1 antibody; Solute carrier family 32 member 1 antibody; Vesicular GABA Amino Acid Transporter antibody; Vesicular GABA transporter antibody; Vesicular inhibitory amino acid transporter antibody; VGAT antibody; VIAAT antibody; VIAAT_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Vesicular inhibitory amino acid transporter protein (14-118AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC32A1 Antibody (CSB-PA863984LA01HU)，的标记方式是Non-conjugated。对于SLC32A1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA863984LB01HU SLC32A1 Antibody, HRP conjugated ELISA
    FITC CSB-PA863984LC01HU SLC32A1 Antibody, FITC conjugated
    Biotin CSB-PA863984LD01HU SLC32A1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the uptake of GABA and glycine into the synaptic vesicles.
  • 基因功能参考文献：
    1. VIATT has been identified in horizontal cells of the adult outer retina in culture, either at their terminals or throughout the entire cell. PMID: 12115694
    2. Subjects with schizophrenia exhibited expression deficits in GABA transpter 1. PMID: 17471287
  • 亚细胞定位：
    Cytoplasmic vesicle membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Amino acid/polyamine transporter 2 family
  • 组织特异性：
    Retina. Expressed throughout the horizontal cells or more specifically at the terminals.
  • 数据库链接：

    HGNC: 11018

    OMIM: 616440

    KEGG: hsa:140679

    STRING: 9606.ENSP00000217420

    UniGene: Hs.179080