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SLC25A32 Antibody

  • 货号：
    CSB-PA872477LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse kidney tissue, Mouse skeletal muscle tissue
      All lanes: SLC25A32 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 36 kDa
      Observed band size: 36 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC25A32 Polyclonal antibody
  • Uniprot No.：
    Q9H2D1
  • 基因名：
    SLC25A32
  • 别名：
    SLC25A32; MFT; MFTC; Mitochondrial folate transporter/carrier; Solute carrier family 25 member 32
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Mitochondrial folate transporter/carrier protein (44-88AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC25A32 Antibody (CSB-PA872477LA01HU)，的标记方式是Non-conjugated。对于SLC25A32 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA872477LB01HU SLC25A32 Antibody, HRP conjugated ELISA
    FITC CSB-PA872477LC01HU SLC25A32 Antibody, FITC conjugated
    Biotin CSB-PA872477LD01HU SLC25A32 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transports folate across the inner membranes of mitochondria. Can also transport FAD across the mitochondrial inner membrane.
  • 基因功能参考文献：
    1. These data demonstrate that the loss of functional Slc25a32 results in cranial neural tube defects (NTDs) in mice and has also been observed in a human NTD patient. PMID: 29666258
    2. A novel SLC25A32 homozygous variant is associated with severe neuromuscular phenotype. PMID: 28443623
    3. SLC25A32 gene polymorphism could be a risk factor for lower folate concentration and future fracture. PMID: 24354357
    4. identified residues in the walls and at the base of the transport cavity that are involved in substrate recognition by the MFT PMID: 21768094
    5. Patient with SLC25A32 deficiency was able to have a successful pregnancy after fertilization in vitro. PMID: 19362304

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  • 相关疾病：
    Exercise intolerance, riboflavin-responsive (RREI)
  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 29683

    OMIM: 610815

    KEGG: hsa:81034

    STRING: 9606.ENSP00000297578

    UniGene: Hs.532265