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SLC25A10 Antibody

  • 货号：
    CSB-PA883371LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: SLC25A10 antibody at 16µg/ml
      Lane 1: Mouse liver tissue
      Lane 2: Mouse kidney tissue
      Lane 3: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 32, 33 kDa
      Observed band size: 32, 24 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA883371LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostata cancer using CSB-PA883371LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC25A10 Polyclonal antibody
  • Uniprot No.：
    Q9UBX3
  • 基因名：
    SLC25A10
  • 别名：
    SLC25A10; DIC; Mitochondrial dicarboxylate carrier; Solute carrier family 25 member 10
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Mitochondrial dicarboxylate carrier protein (124-162AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC25A10 Antibody (CSB-PA883371LA01HU)，的标记方式是Non-conjugated。对于SLC25A10 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA883371LB01HU SLC25A10 Antibody, HRP conjugated ELISA
    FITC CSB-PA883371LC01HU SLC25A10 Antibody, FITC conjugated
    Biotin CSB-PA883371LD01HU SLC25A10 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane.
  • 基因功能参考文献：
    1. study identifies novel genes associated with insulin sensitivity in adipocytes in women independently of obesity. KFL15 and SLC25A10 are inhibitors of insulin-stimulated lipogenesis under conditions when glucose transport is the rate limiting step PMID: 28570579
    2. the SLC25A10 carrier plays an important role in regulating redox homeostasis to protect confluent cells against oxidative stress. PMID: 25797253
    3. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
    4. SLC25A10 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    5. Slc25a10 plays an important role in supplying malate for citrate transport required for fatty acid synthesis and its inhibition might effectively reduce lipid accumulation in adipose tissues PMID: 16027120

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  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 组织特异性：
    Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed.
  • 数据库链接：

    HGNC: 10980

    OMIM: 606794

    KEGG: hsa:1468

    STRING: 9606.ENSP00000345580

    UniGene: Hs.548187