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SLC16A10 Antibody

  • 中文名称：
    SLC16A10兔多克隆抗体
  • 货号：
    CSB-PA851563HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA851563HA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA851563HA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA851563HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC16A10 Polyclonal antibody
  • Uniprot No.：
    Q8TF71
  • 基因名：
    SLC16A10
  • 别名：
    SLC16A10 antibody; MCT10 antibody; TAT1 antibody; Monocarboxylate transporter 10 antibody; MCT 10 antibody; Aromatic amino acid transporter 1 antibody; Solute carrier family 16 member 10 antibody; T-type amino acid transporter 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Monocarboxylate transporter 10 protein (159-201AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC16A10 Antibody (CSB-PA851563HA01HU)，的标记方式是Non-conjugated。对于SLC16A10 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA851563HB01HU SLC16A10 Antibody, HRP conjugated ELISA
    FITC CSB-PA851563HC01HU SLC16A10 Antibody, FITC conjugated
    Biotin CSB-PA851563HD01HU SLC16A10 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sodium-independent transporter that mediates the uptake of aromatic acids. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells.
  • 基因功能参考文献：
    1. In the MCT10 modeled structure, N81 appeared to protrude into the putative trajectory of tryptophan. PMID: 28754537
    2. the aim of this study was to examine if MCT8 and MCT10 increase the availability of triiodothyronine for its nuclear receptor. PMID: 27492966
    3. High TAT1 expression is associated with metastasis and recurrence in endometrial cancer. PMID: 26779635
    4. monocarboxylate transporter 10 facilitates bromoacetyl [(125)I] iodothyronine transport, but is not labeled by it PMID: 21315799
    5. Increased MCT8 and decreased MCT10 expression within placentae of pregnancies complicated by IUGR may contribute to aberrant development of the fetoplacental unit. PMID: 20167367
    6. MCT10 is at least as active a thyroid hormone transporter as hMCT8, and that both transporters facilitate iodothyronine uptake as well as efflux. PMID: 18337592

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Basolateral cell membrane.
  • 蛋白家族：
    Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
  • 组织特异性：
    Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.
  • 数据库链接：

    HGNC: 17027

    OMIM: 607550

    KEGG: hsa:117247

    STRING: 9606.ENSP00000357844

    UniGene: Hs.591327