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SLC13A4 Antibody

  • 货号：
    CSB-PA891949LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: SLC13A4 antibody at 2μg/ml + 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 69 kDa
      Observed band size: 69 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA891949LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA891949LA01HU at dilution of 1:100
    • Immunofluorescent analysis of 293 cells using CSB-PA891949LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC13A4 Polyclonal antibody
  • Uniprot No.：
    Q9UKG4
  • 基因名：
    SLC13A4
  • 别名：
    Na(+)/sulfate cotransporter SUT-1 antibody; NaS2 antibody; S13A4_HUMAN antibody; SLC13A4 antibody; Solute carrier family 13 member 4 antibody; SUT1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Solute carrier family 13 member 4 protein (134-273AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC13A4 Antibody (CSB-PA891949LA01HU)，的标记方式是Non-conjugated。对于SLC13A4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA891949LB01HU SLC13A4 Antibody, HRP conjugated ELISA
    FITC CSB-PA891949LC01HU SLC13A4 Antibody, FITC conjugated
    Biotin CSB-PA891949LD01HU SLC13A4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV).
  • 基因功能参考文献：
    1. Study found that despite differential expression of the two SLC13A4 transcripts, no detectable functional difference in the cellular sorting or sulfate transporting was found. However, some variants can influence both mechanism in specific cell membranes. This is like to have clinical implications based on the consequences of impaired sulfate transport during pregnancy in rodent models. PMID: 28385533
    2. SLC13A4 and SLC26A2 were the most abundant sulfate transporter mRNAs, which localized to syncytiotrophoblast and cytotrophoblast cells, respectively. PMID: 23453247
    3. To investigate the regulation of SLC13A4 gene expression, we analysed the transcriptional activity of the SLC13A4 5'-flanking region in the JEG-3 placental cell line using luciferase reporter assays. PMID: 23485456
    4. Here, we characterized the functional properties of the human Na(+)-sulfate cotransporter (hNaS2), determined its tissue distribution, and identified its gene (SLC13A4) structure. PMID: 15607730
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SLC13A/DASS transporter (TC 2.A.47) family, NADC subfamily
  • 组织特异性：
    Highly expressed in placenta and testis with intermediate levels in brain and lower levels in heart, thymus and liver.
  • 数据库链接：

    HGNC: 15827

    OMIM: 604309

    KEGG: hsa:26266

    STRING: 9606.ENSP00000297282

    UniGene: Hs.490241