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SKOR1 Antibody

  • 货号：
    CSB-PA308064HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA308064HA01HU diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SKOR1 Polyclonal antibody
  • Uniprot No.：
    P84550
  • 基因名：
    SKOR1
  • 别名：
    SKOR1 antibody; CORL1 antibody; FUSSEL15 antibody; LBXCOR1 antibody; SKI family transcriptional corepressor 1 antibody; Functional Smad-suppressing element on chromosome 15 antibody; Fussel-15 antibody; LBX1 corepressor 1 antibody; Ladybird homeobox corepressor 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human SKI family transcriptional corepressor 1 protein (744-965AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SKOR1 Antibody (CSB-PA308064HA01HU)，的标记方式是Non-conjugated。对于SKOR1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA308064HB01HU SKOR1 Antibody, HRP conjugated ELISA
    FITC CSB-PA308064HC01HU SKOR1 Antibody, FITC conjugated
    Biotin CSB-PA308064HD01HU SKOR1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a transcriptional corepressor of LBX1. Inhibits BMP signaling.
  • 基因功能参考文献：
    1. Permanent expression of Fussel-15 in keloid and skin sclerosis fibroblasts could be involved in the pathogenesis of these conditions. PMID: 21641385
    2. a novel gene, fussel-15 (functional smad suppressing element on chromosome 15) with high homology to the recently discovered Fussel-18 protein. PMID: 17292623
    3. MEIS1 and LBXCOR1 are developmental factors and raise new pathophysiologic questions for RLS. PMID: 18541116
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 19822783
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19279021
    6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 17637780

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    SKI family
  • 组织特异性：
    Present specifically in cerebellar Purkinje cells (at protein level).
  • 数据库链接：

    HGNC: 21326

    OMIM: 611273

    KEGG: hsa:390598

    STRING: 9606.ENSP00000369374

    UniGene: Hs.451224