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SIGLEC12 Antibody

  • 货号：
    CSB-PA836278ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA836278ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SIGLEC12 Polyclonal antibody
  • Uniprot No.：
    Q96PQ1
  • 基因名：
    SIGLEC12
  • 别名：
    SIGLEC12 antibody; SIGLECL1 antibody; SLG antibody; UNQ9215/PRO34042Sialic acid-binding Ig-like lectin 12 antibody; Siglec-12 antibody; Sialic acid-binding Ig-like lectin-like 1 antibody; Siglec-L1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Sialic acid-binding Ig-like lectin 12 protein (20-210AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
  • 基因功能参考文献：
    1. cardiovascular outcomes may differ based on SIGLEC12 genotype, and antihypertensive treatment strategy. PMID: 23690342
    2. SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. PMID: 21555517
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family
  • 组织特异性：
    Isoform Short is highly expressed in spleen, small intestine and adrenal gland; it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal chord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow;
  • 数据库链接：

    HGNC: 15482

    OMIM: 606094

    KEGG: hsa:89858

    STRING: 9606.ENSP00000291707

    UniGene: Hs.249741