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SHISA5 Antibody

  • 货号：
    CSB-PA818677LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA818677LA01HU at dilution of 1:100
    • Immunofluorescence staining of A549 cells with CSB-PA818677LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunoprecipitating SHISA5 in HepG2 whole cell lysate
      Lane 1: Rabbit control IgG (1µg) instead of CSB-PA818677LA01HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA818677LA01HU (6µg) + HepG2 whole cell lysate (500µg)
      Lane 3: HepG2 whole cell lysate (10µg)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SHISA5 Polyclonal antibody
  • Uniprot No.：
    Q8N114
  • 基因名：
  • 别名：
    SHISA5 antibody; SCOTIN antibody; PSEC0133 antibody; Protein shisa-5 antibody; Putative NF-kappa-B-activating protein 120 antibody; Scotin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein shisa-5 protein (56-137AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SHISA5 Antibody (CSB-PA818677LA01HU)，的标记方式是Non-conjugated。对于SHISA5 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA818677LB01HU SHISA5 Antibody, HRP conjugated ELISA
    FITC CSB-PA818677LC01HU SHISA5 Antibody, FITC conjugated
    Biotin CSB-PA818677LD01HU SHISA5 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF, IP
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:500
    IP 1:200-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
  • 基因功能参考文献：
    1. IFN-beta-induced SCOTIN recruits the HCV NS5A protein to autophagosomes for degradation, thereby restricting HCV replication. PMID: 26868272
    2. Scotin plays a role in p53-dependent apoptosis PMID: 12135983
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane.
  • 蛋白家族：
    Shisa family
  • 数据库链接：

    HGNC: 30376

    OMIM: 607290

    KEGG: hsa:51246

    STRING: 9606.ENSP00000296444

    UniGene: Hs.414579