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SH3GLB2 Antibody

  • 货号：
    CSB-PA002346
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COS7 cells using Endophilin B2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9NR46
  • 基因名：
  • 别名：
    Endophilin B2 antibody; Endophilin-B2 antibody; OTTHUMP00000022320 antibody; PP6569 antibody; PP9455 antibody; Retinoid receptor induced gene 1 antibody; RRIG1 antibody; SH3 containing protein SH3GLB2 antibody; SH3 domain GRB2 like endophilin B2 antibody; SH3 domain-containing GRB2-like protein B2 antibody; SH3GLB2 antibody; SHLB2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat,Monkey
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Endophilin B2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Here the s report that Endophilin B2, similarly to Endophilin B1, plays an indispensable role in mitochondria sequestration and inner mitochondrial membrane (IMM) protein degradation during mitophagy. PMID: 27112121
    2. Data (including data from studies in knockout mice) suggest that SH3GLB2 regulates trafficking of endocytic vesicles and autophagosomes to late endosomes or lysosomes; despite having an intracellular localization and tissue distribution similar to endophilin B1, endophilin B2 is dispensable for mitochondrial apoptosis. PMID: 28455444
    3. the potential importance of the endophilin B2-plectin complex in the biological functions depending on nuclear migration and positioning. PMID: 23921385
    4. identified a nonmutated HLA-A2-binding epitope in the human ortholog SH3GLB2, which primed T cells from healthy HLA-A2(+) individuals PMID: 18303116
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Endophilin family
  • 组织特异性：
    Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.
  • 数据库链接：

    HGNC: 10834

    OMIM: 609288

    KEGG: hsa:56904

    STRING: 9606.ENSP00000361640

    UniGene: Hs.460238