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SFXN4 Antibody

  • 货号：
    CSB-PA744046LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: SFXN4 antibody at 0.3µg/ml
      Lane 1: K562 whole cell lysate
      Lane 2: U251 whole cell lysate
      Lane 3: U87 whole cell lysate
      Lane 4: A549 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 38, 35, 25 kDa
      Observed band size: 38 kDa
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA744046LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human thymus tissue using CSB-PA744046LA01HU at dilution of 1:100
    • Immunofluorescent analysis of U251 cells using CSB-PA744046LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：
    SFXN4 polyclonal antibody CSB-PA744046LA01HU was produced in rabbit immunized by using the Recombinant Human Sideroflexin-4 protein (2-110AA) as the immunogen. The target protein SFXN4 a member of the sideroflexin family, is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. It is not able to mediate transport of serine into mitochondria. Diseases associated with SFXN4 include Combined Oxidative Phosphorylation Deficiency 18 and Macrocytic Anemia.
    This Rabbit anti-Homo sapiens (Human) SFXN4 Polyclonal antibody was tested in the ELISA, IHC, IF and WB applications. The non-conjugated IgG was purified by antigen affinity. It only reacts with the SFXN4 proteins of human origin and may be used to detect the endogenous levels of SFXN4 protein.
  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SFXN4 Polyclonal antibody
  • Uniprot No.：
    Q6P4A7
  • 基因名：
    SFXN4
  • 别名：
    SFXN4; BCRM1; Sideroflexin-4; Breast cancer resistance marker 1
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Sideroflexin-4 protein (2-110AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SFXN4 Antibody (CSB-PA744046LA01HU)，的标记方式是Non-conjugated。对于SFXN4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA744046LB01HU SFXN4 Antibody, HRP conjugated ELISA
    FITC CSB-PA744046LC01HU SFXN4 Antibody, FITC conjugated
    Biotin CSB-PA744046LD01HU SFXN4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mitochondrial amino-acid transporter. Does not act as a serine transporter: not able to mediate transport of serine into mitochondria.
  • 基因功能参考文献：
    1. Our findings establish mutations in SFXN4 as a cause of mitochondriopathy and macrocytic anemia. PMID: 24119684
    2. we isolated a cDNA encoding a novel sideroflexin protein (SFXN4), which showed 59% identity and 71% similarity to mouse sideroflexin4. PMID: 14756423
  • 相关疾病：
    Combined oxidative phosphorylation deficiency 18 (COXPD18)
  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Sideroflexin family
  • 数据库链接：

    HGNC: 16088

    OMIM: 615564

    KEGG: hsa:119559

    STRING: 9606.ENSP00000347924

    UniGene: Hs.655168