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SEZ6L Antibody

  • 货号：
    CSB-PA115417
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA115417(SEZ6L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9BYH1
  • 基因名：
    SEZ6L
  • 别名：
    SEZ6L antibody; KIAA0927 antibody; UNQ2542/PRO6094Seizure 6-like protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human SEZ6L
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May contribute to specialized endoplasmic reticulum functions in neurons.
  • 基因功能参考文献：
    1. This is the first demonstration that genetic variants in the SEZ6L gene are associated with bipolar disorder Iin female patients and provides additional compelling evidence for genetic variation at 22q11-13 that influences BD-I risk. PMID: 22920719
    2. the addition of SEZ6L improved the performance of the Liverpool Lung Project risk model. PMID: 20424129
    3. A role of the SEZ6L Met430Ile polymorphic variant in increasing lung cancer risk. PMID: 17804757
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    SEZ6 family
  • 组织特异性：
    Widely expressed, including adult and fetal brains and lungs. Not expressed in all lung cancer cell lines.
  • 数据库链接：

    HGNC: 10763

    OMIM: 607021

    KEGG: hsa:23544

    STRING: 9606.ENSP00000248933

    UniGene: Hs.194766