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SERPINB14 Antibody

  • 货号：
    CSB-PA004301E01CH
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: SERPINB14 antibody at 2µg/ml
      Lane 1: Ovalbumin at 1: 4000
      Lane 2: Ovalbumin at 1: 8000
      Lane 3: Ovalbumin at 1: 16000
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 46 kDa
      Observed band size: 46 kDa
  • 其他：

产品详情

  • 产品描述：

    The SERPINB14 polyclonal antibody was prepared by immunizing rabbits with chicken Ovalbumin. The antibody was then affinity purified using the antigen and tested in both ELISA and WB applications. The SERPINB14 polyclonal antibody is capable of reacting with samples from Gallus gallus (Chicken) species.

    In ELISA, the SERPINB14 polyclonal antibody can be used to detect the presence and quantity of Ovalbumin in a sample by measuring the absorbance of the antibody-antigen complex. In WB, this antibody can be used to identify the presence and relative molecular weight of Ovalbumin in a chicken sample through protein separation by size and immunoblotting.

  • 产品名称：
    Rabbit anti-Chicken SERPINB14 Polyclonal antibody
  • Uniprot No.：
    P01012
  • 基因名：
    SERPINB14
  • 别名：
    Allergen Gal d II antibody; Egg albumin antibody; OVAL_CHICK antibody; Ovalbumin antibody; Plakalbumin antibody; Serpin peptidase inhibitor antibody; SERPINB14 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Chicken
  • 免疫原：
    Chicken Ovalbumin (Native Protein)
  • 免疫原种属：
    Chicken
  • 标记方式：
    Non-conjugated

    本页面中的产品，SERPINB14 Antibody (CSB-PA004301E01CH)，的标记方式是Non-conjugated。对于SERPINB14 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA004301F01CH SERPINB14 Antibody, HRP conjugated ELISA
    FITC CSB-PA004301G01CH SERPINB14 Antibody, FITC conjugated
    Biotin CSB-PA004301H01CH SERPINB14 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Non-inhibitory serpin. Storage protein of egg white.
  • 基因功能参考文献：
    1. 120A and C30/73/120A mutants formed no SS form, in contrast to C73/120A as a control. Thus, we concluded that Cys30 participates in the correct folding of OVA, and that its SS bond (Cys11-Cys30) is transiently generated during the early folding stage to avoid misfolding, and then the native SS form of OVA is regenerated through SH-SS exchanges. PMID: 29175210
    2. Data show that both ovalbumin and ovomucoid were efficiently mutagenized in cultured primordial germ cells (PGCs) by CRISPR/Cas9 system. PMID: 27050479
    3. Data show that both green and red light wavelengths induce structural changes in ovalbumin. PMID: 26656181
    4. found that ovalbumin packs into a bicontinuous structure with a significant void space and that ovalbumin is highly ordered within the dense network PMID: 26488663
    5. Cluster analysis revealed a first group of proteins related to mineralization and mainly present at the onset of calcification including OVOT, OVAL, OC-17, and two novel calcium binding proteins (EDIL3, MFGE8). PMID: 25284052
    6. Secondary and tertiary structures of OVA were characterised to show the relationship between potential allergenicity and the conformation of OVA after heating and glycation. PMID: 23915026
    7. Inhalation tolerance limits aeroallergen OVA peptide capture by airway mucosal dendritic cell subsets via a mechanism of bone marrow suppression of dendritic cell precursor function coupled with reduced antigen availability in vivo at the airway mucosa. PMID: 21930961
    8. Lysozyme (pI = 9.3) destabilizes the liquid amorphous calcium carbonate emulsion whereas the glycoprotein ovalbumin (pI = 4.7) extends the lifespan of the emulsified state remarkably. PMID: 21736300
    9. Fibrosarcoma-secreting vesicle-bound ovalbumin elicits a strong antigen-specific CD8-type T cell response, CD4-positive T cell help, antigen-specific antibodies, and a decrease in the percentage of immunosuppressive regulatory T cells in the tumor. PMID: 21705625
    10. The presence of the original SS bridge in ovalbumin contributes to conformational stability but is not directly related to the conversion to heat-stable ovalbumin (S-OVA). PMID: 21389617
    11. These s report the kinetics for the rate of acetylation during protein synthesis using ovalabumin. PMID: 272676
    12. Reports details of the organization of the ovalbumin gene exon-intron structure. PMID: 283395
    13. s measure the kinetics of mRNA binding to microsomes during translation & nascent chain elongation rates. PMID: 6749856
    14. Demonstrates the kinetics of I-ovalbumin conformer serine peptidase inhibition. PMID: 8939987
    15. Demonstrates that the I-ovalabumin conformer binds bovine trypsin PMID: 15488772
    16. Results provide a detailed equilibrium and kinetic characterization of the interaction between the serpin ovalbumin and bovine trypsin. PMID: 15488772
    17. the carbohydrate chain and two phosphate moieties do not affect hydrophobic collapse in the kinetic refolding of hen ovalbumin but play an important role in the slow rearrangement, by blocking the off-pathway reaction that competes with correct refolding PMID: 15618616
    18. Chromatin immunoprecipitation assays showed that the ovalbumin control region was associated with acetylated histone H3 but not with dimethylated histone H3 at Lys 27. PMID: 16794325
    19. Intracerebral, but not systemic, infection with attenuated Listeria-secreting ovalbumin induces a neurological model syndrome in transgenic neuron-specific enolase-OVA mice after brain bacterial clearance, whereas wild-type mice remain healthy. PMID: 18523310

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Serpin family, Ov-serpin subfamily
  • 组织特异性：
    Major protein of egg white. Expressed in the magnum of the oviduct (at protein level).
  • 数据库链接：

    KEGG: gga:396058

    STRING: 9031.ENSGALP00000036403

    UniGene: Gga.623