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SERPINA9 Antibody

  • 货号：
    CSB-PA022029
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA022029(SERPINA9 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA022029(SERPINA9 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 293T cells, 231 cells, U937 cells, Raji cells, Primary antibody: CSB-PA022029(SERPINA9 Antibody) at dilution 1/337.5, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q86WD7
  • 基因名：
    SERPINA9
  • 别名：
    Centerin antibody; GCET1 antibody; Germinal center B cell expressed transcript 1 antibody; Germinal center B-cell-expressed transcript 1 protein antibody; Seprin A9 antibody; Serine proteinase inhibitor A11 antibody; Serpin A9 antibody; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 9 antibody; Serpin peptidase inhibitor clade A member 9 antibody; SERPINA11 antibody; SERPINA11b antibody; Serpina9 antibody; SPA9_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide of Human SERPINA9
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro).
  • 基因功能参考文献：
    1. Diagnostic Utility of the Germinal Center-associated Markers GCET1, HGAL, and LMO2 in Hematolymphoid Neoplasms. PMID: 25203428
    2. Results report the cloning of germinal center B-cell expressed transcripts 1 and 2 (GCET1 and 2), and show that both are expressed in follicular lymphoma and diffuse large B-cell lymphoma with germinal center B-cell differentiation. PMID: 12819018
    3. The cloning, expression and molecular characterization of recombinant serpina9 (centerin) are reported. PMID: 17447896
    4. Gcet-1 protein expression is restricted to a subset of germinal center B cells, establishing the existence of a distinct heterogeneity among normal and neoplastic germinal center B cells PMID: 17898315
    5. Immunohistochemical expression of centerin further defines the germinal center cell origin of a subgroup of lymphomas. PMID: 18550480
    6. serpinA9 was associated with stroke in both whites and blacks PMID: 18799872
    7. Observational study of gene-disease association. (HuGE Navigator) PMID: 19023099
    8. Observational study of gene-disease association. (HuGE Navigator) PMID: 17975119

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  • 亚细胞定位：
    [Isoform 1]: Secreted.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.; [Isoform 5]: Cytoplasm.; [Isoform 6]: Cytoplasm.; [Isoform 7]: Membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Serpin family
  • 组织特异性：
    Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies.
  • 数据库链接：

    HGNC: 15995

    OMIM: 615677

    KEGG: hsa:327657

    STRING: 9606.ENSP00000337133

    UniGene: Hs.317970