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SERINC3 Antibody

  • 货号：
    CSB-PA984539
  • 规格：
    ￥2024
  • 图片：
    • Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.
    • Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/40.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SERINC3 Polyclonal antibody
  • Uniprot No.：
    Q13530
  • 基因名：
    SERINC3
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide corresponding to a region derived from internal residues of Human serine incorporator 3
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm.
  • 基因功能参考文献：
    1. SERINC3 and SERINC5 together restricted HIV-1 replication, and this restriction was evaded by Nef PMID: 26416733
    2. TDE1 inhibits apoptosis and stimulates tumorigenesis PMID: 16547497
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.; Cytoplasm, perinuclear region.
  • 蛋白家族：
    TDE1 family
  • 组织特异性：
    Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.
  • 数据库链接：

    HGNC: 11699

    OMIM: 607165

    KEGG: hsa:10955

    STRING: 9606.ENSP00000255175

    UniGene: Hs.272168