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SEPT5 Antibody

  • 货号：
    CSB-PA030106
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q99719
  • 基因名：
    SEPT5
  • 别名：
    5 Sep antibody; CDCrel 1 antibody; CDCREL antibody; CDCrel-1 antibody; CDCREL1 antibody; Cell division control related protein 1 antibody; Cell division control-related protein 1 antibody; H5 antibody; HCDCREL 1 antibody; OTTHUMP00000197271 antibody; OTTHUMP00000197272 antibody; OTTHUMP00000197273 antibody; OTTHUMP00000197274 antibody; OTTHUMP00000197275 antibody; OTTHUMP00000197276 antibody; OTTHUMP00000197396 antibody; OTTHUMP00000197410 antibody; Peanut like 1 antibody; Peanut like 1 homolog antibody; Peanut like protein 1 antibody; Peanut-like protein 1 antibody; Platelet glycoprotein Ib beta chain antibody; PNUTL1 antibody; SEPT5 antibody; SEPT5_HUMAN antibody; Septin 5 antibody; Septin-5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Septin 5.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion.
  • 基因功能参考文献：
    1. CDCrel-1 overexpression exerts dopamine-dependent neurotoxicity and may contribute to the development of autosomal-recessive juvenile parkinsonism PMID: 14530399
    2. We studied the assembly of three human septins, SEPT4, SEPT5 and SEPT8, with each other (heterotypic) and with themselves (homotypic) using a yeast two-hybrid system. PMID: 15214843
    3. the high expression levels of PNUTL1 in human pancreatic endocrine cells that suggests a similar role of this protein in islet cells to that demonstrated in neuronal tissues, and warrants further functional studies of this protein. PMID: 16179808
    4. Our finding suggests a role for members of the septin family in the development of proliferative retinal membranes. PMID: 17625225
    5. HSP70 and constitutively active HSF1 mediate protection against CDCrel-1-mediated toxicity PMID: 18398426

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  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 组织特异性：
    Expressed at high levels in the CNS, as well as in heart and platelets (at protein level).
  • 数据库链接：

    HGNC: 9164

    OMIM: 602724

    KEGG: hsa:5413

    STRING: 9606.ENSP00000391311

    UniGene: Hs.728762