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SEPT3 Antibody

  • 货号：
    CSB-PA004068
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293 cells using Septin 3 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9UH03
  • 基因名：
    SEPT3
  • 别名：
    bK250D10.3 antibody; MGC133218 antibody; Neuronal specific septin 3 antibody; Neuronal-specific septin-3 antibody; OTTHUMP00000028742 antibody; SEP 3 antibody; SEP3 antibody; SEPT 3 antibody; sept3 antibody; SEPT3 protein antibody; SEPT3_HUMAN antibody; Septin3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Septin 3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
  • 基因功能参考文献：
    1. SUMOylation of human septins is critical for septin filament bundling and cytokinesis. PMID: 29051266
    2. Data indicate that forchlorfenuron (FCF) exhibits differential binding preference for septins SEPT2 and SEPT3. PMID: 24787956
    3. septins from the SEPT3 subgroup may be important determinants of polymerization by occupying the terminal position in octameric units which themselves form the building blocks of at least some heterofilaments PMID: 23163726
    4. Data show that Septins of the SEPT6 group preferentially interacted with septins of the SEPT2 group, SEPT3 group and SEPT7 group. PMID: 21082023
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, synapse.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 组织特异性：
    Brain-specific.
  • 数据库链接：

    HGNC: 10750

    OMIM: 608314

    KEGG: hsa:55964

    STRING: 9606.ENSP00000379704

    UniGene: Hs.120483