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SEMA3G Antibody

  • 货号：
    CSB-PA223916
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA223916(SEMA3G Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9NS98
  • 基因名：
    SEMA3G
  • 别名：
    FLJ00014 antibody; MGC119473 antibody; Sem2 antibody; SEM3G_HUMAN antibody; Sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3G antibody; Sema3g antibody; Semaphorin 3G antibody; Semaphorin sem2 antibody; Semaphorin-3G antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Fusion protein of Human SEMA3G
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has chemorepulsive activities for sympathetic axons. Ligand of NRP2.
  • 基因功能参考文献：
    1. Results indicate that Sema3G protein is secreted by podocytes and protects them from inflammatory kidney diseases and diabetic nephropathy. PMID: 27180624
    2. Results identify Sema3g as one of the downstream effectors of PPAR-gamma, which is centrally involved in regulating endothelial cell migration. PMID: 25335934
    3. overexpressed SEMA3G inhibited the migratory and invasive behavior of U251MG cancer cells PMID: 22562223
    4. Identify Sema3G as a primarily endothelial cell-expressed class 3 semaphorin that controls endothelial and smooth muscle cell functions in autocrine and paracrine manners. PMID: 20947821
    5. In gliomas, SEMA3B, SEMA3G and NRP2 expressions were related to prolonged survival PMID: 18781179
    6. Sema3G inhibits tumor progression from MDA-MB-435 but not from MDA-MB-231 cancer cells. It inhibits tumor angiogenesis in MDA-MB-231 cells. PMID: 18818766

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Semaphorin family
  • 数据库链接：

    HGNC: 30400

    KEGG: hsa:56920

    STRING: 9606.ENSP00000231721

    UniGene: Hs.59729