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SEC61G Antibody

  • 货号：
    CSB-PA03509A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA03509A0Rb at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SEC61G Polyclonal antibody
  • Uniprot No.：
    P60059
  • 基因名：
  • 别名：
    SEC61G; Protein transport protein Sec61 subunit gamma
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein transport protein Sec61 subunit gamma protein (1-32AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SEC61G Antibody (CSB-PA03509A0Rb)，的标记方式是Non-conjugated。对于SEC61G Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA03509B0Rb SEC61G Antibody, HRP conjugated ELISA
    FITC CSB-PA03509C0Rb SEC61G Antibody, FITC conjugated
    Biotin CSB-PA03509D0Rb SEC61G Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER.
  • 基因功能参考文献：
    1. Sequencing of childhood ependymoma samples indicate Sec61 gamma subunit protein (SEC61G)-epidermal growth factor receptor (EGFR) chimeric mRNAs in one infratentorial ependymoma , arguing that this fusion occurs in a small proportion of these tumors. PMID: 29092923
    2. Cotransin, a substrate-selective Sec61 inhibitor, traps nascent transmembrane domains in the cytosolic vestibule, permitting detailed interrogation of an early pre-integration intermediate. PMID: 24497544
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    SecE/SEC61-gamma family
  • 数据库链接：

    HGNC: 18277

    OMIM: 609215

    KEGG: hsa:23480

    STRING: 9606.ENSP00000341538

    UniGene: Hs.488282