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SEC24A Antibody

  • 货号：
    CSB-PA020950GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O95486
  • 基因名：
  • 别名：
    SEC24A antibody; Protein transport protein Sec24A antibody; SEC24-related protein A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SEC24A
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
  • 基因功能参考文献：
    1. the association between Kv1.3 and the COPII cargo adaptor subunit isoform Sec24a PMID: 26156069
    2. CstA, a secreted Brucella protein specifically interacts with human Sec24A. PMID: 22820839
    3. Sec24 isoforms expand the repertoire of cargo for signal-mediated ER export, but are in part functionally redundant. PMID: 17255961
  • 亚细胞定位：
    Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
  • 蛋白家族：
    SEC23/SEC24 family, SEC24 subfamily
  • 数据库链接：

    HGNC: 10703

    OMIM: 607183

    KEGG: hsa:10802

    STRING: 9606.ENSP00000381823

    UniGene: Hs.595540