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SEC23IP Antibody

  • 货号：
    CSB-PA896767LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate
      All lanes: SEC23IP antibody at 2.7µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 112, 103 kDa
      Observed band size: 112 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA896767LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA896767LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA896767LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SEC23IP Polyclonal antibody
  • Uniprot No.：
    Q9Y6Y8
  • 基因名：
    SEC23IP
  • 别名：
    MSTP053 antibody; p125 antibody; P125A antibody; Phospholipase antibody; S23IP_HUMAN antibody; Sec23 interacting protein p125 antibody; SEC23-interacting protein antibody; SEC23IP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human SEC23-interacting protein (779-989AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SEC23IP Antibody (CSB-PA896767LA01HU)，的标记方式是Non-conjugated。对于SEC23IP Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA896767LB01HU SEC23IP Antibody, HRP conjugated ELISA
    FITC CSB-PA896767LC01HU SEC23IP Antibody, FITC conjugated
    Biotin CSB-PA896767LD01HU SEC23IP Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
  • 基因功能参考文献：
    1. A basic cluster and a hydrophobic interface in the DDHD and SAM domains, respectively, are required for p125A-mediated functional endoplasmic reticulum exit site assembly. PMID: 24522181
    2. Xenopus sec23ip is required for normal neural crest cell development, suggesting a role for the human ortholog in Waardenburg syndrome neural crest defects. PMID: 20308572
    3. The results suggest that p125A is part of the Sec13/Sec31A subcomplex and facilitates ER export in mammalian cells. PMID: 20679433
    4. p125 is a mammalian-specific component of ER exit sites and participates in the organization of this compartment PMID: 15623529
  • 亚细胞定位：
    Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum.
  • 蛋白家族：
    PA-PLA1 family
  • 组织特异性：
    Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.
  • 数据库链接：

    HGNC: 17018

    OMIM: 617852

    KEGG: hsa:11196

    STRING: 9606.ENSP00000358071

    UniGene: Hs.435004